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CRITIQUES of ALTERED NUCLEAR TRANSFER (ANT) and OOCYTE ASSISTED REPROGRAMMING (OAR)

In December 2004, Dr. William Hurlbut presented the President's Council for Bioethics with a proposal for Altered Nuclear Transfer (ANT). The proposal, which claimed to offer a technique for producing pluripotent stem cells without creating, and then destroying, an embryo in the process, is outlined in the President's Council for Bioethics' White Paper. For more information about ANT and its supporters, please visit its website.

Communio has published a series of philosophical, moral, and biological critiques of the ANT proposal.

PART I appeared in the Winter 2004 issue.

Roberto Colombo: Altered Nuclear Transfer as an Alternative Way to Human Embryonic Stem Cells: Biological and Moral Notes
Adrian J. Walker: Altered Nuclear Transfer: A Philosophical Critique

PART II

Fr. Nicanor Austriaco, O.P., offered a defense of ANT in response to Adrian Walker's critique. This defense and Walker's response were published in the Spring 2005 issue of Communio:

Nicanor Pier Giorgio Austriaco, O.P.: Altered Nuclear Transfer: A Critique of a Critique
Adrian J. Walker: The Primacy of the Organism: Response to Nicanor Austriaco

The same issue published a critique of a variant of ANT known as Oocyte Assisted Reprogramming (OAR). The article was written in response to a Joint Statement on OAR, endorsed by a number of Catholic theologians and ethicists.

Adrian J. Walker: A Way Around the Cloning Objection Against ANT? A Brief Response to the Joint Statement on the Production of Pluripotent Stem Cells by Oocyte Assisted Reprogramming

Part II ended with an article defining theological and philosophical parameters for considering ANT based on criteria provided by Veritatis splendor for the grounding of bioethics.

David L. Schindler: Veritatis Splendor and the Foundations of Bioethics: Notes Toward an Assessment of Altered Nuclear Transfer (ANT) and Embryonic (Pluripotent) Stem Cell Research

PART III

The third installment in this series is David L. Schindler's response (July 2005) to the Joint Statement. Published in Communio 32, no. 2 (Summer 2005)

David L. Schindler: A Response to the Joint Statement, "Production of Pluripotent Stem Cells by Oocyte Assisted Reprogramming"

PART IV

David L. Schindler: "Letter to the Editor" in Crisis, (April, 2006), in response to the article Anti-Science? Pro-Life Dream Team Confronts Embryonic Stem-Cell Juggernaut in Crisis (January, 2006).

PART V

Further responses and discussion appear in the Winter, 2005 issue.

José Granados: ANT-OAR: Is Its Underlying Philosophy of Biology Sound?
Stuart W. Swetland and William L. Saunders: Joint Statement on the OAR Proposal: A Response to Criticisms.
E. Christian Brugger: ANT-OAR: A Morally Acceptable Means for Deriving Pluripotent Stem Cells. A Reply to Criticisms
Adrian J. Walker: Reasonable Doubts. A Reply to E. Christian Brugger
Adrian J. Walker: Who Are the Real Aristotelians? A Response to Edward J. Furton
David L. Schindler: Agere sequitur esse: What Does It Mean? A Response to Father Austriaco